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Further research is necessary to clarify the mechanisms through which Hcy impacts vascular health and to devise more effective therapeutic strategies for disorders associated with HHcy

Moreover, the ability of polyphenols to penetrate the BBB is compound specific and often suboptimal, necessitating advanced delivery strategies such as nanoformulations or prodrugs to enhance CNS targeting (Ramakrishna et al

TGF--dependent signaling, activated by soluble endoglin and growth differentiation factor 15, promotes inflammatory chemokines in the ovary and pelvic adhesions, contributing to reduced fertility (44)

Its return to normal in liver disease is an excellent indicator

As a consequence of the metabolic derangements in diabetes, various complications develop including both macro- and micro-vascular dysfunctions (Duckworth,
