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Description
Epigenetic regulation of macrophages: from homeostasis maintenance to host defense
doi: 10.3390/ijms140611607
The first is Lfgren syndrome, which is characterized by hilar lymphadenopathy, erythema nodosum, arthritis and fever
PMID 37060552
The A549 cell line, resistant to cisplatin treatment, shows a somatic mutation at the first Kelch domain of KEAP1, necessary for its interaction with NRF2, and also methylated promoter, both features that could explain the high levels of NRF2 protein in this cell line 35
