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The prevailing hypothesis is that the accumulation of A peptide triggers a cascade of events that leads to tau hyperphosphorylation, tangle formation, neuronal dysfunction, and finally symptom development [82]

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PloS One 12 (2), e0171285

170 LiS.YenL.PastorW

Its common after microneedling, RF treatments, or PRP when the body needs extra support
