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135 In addition to triggering the MCT1/NF-B/IL-8 pathway, it was also found that lactate promotes angiogenesis by stimulating the phosphoinositide 3-kinase/protein kinase B signaling (PI3K/Akt) pathway

doi: 10.1016/j.immuni.2020.07.002 187 KonishiASuzukiJKuwaharaMMatsumotoANomuraSSogaTet al

Theres no evidence that sermorelin, or any growth hormonestimulating peptide, raises estrogen levels
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Breast and lung cancer cells can exploit redox-sensitive transient receptor potential cation channel subfamily A member 1 (TRPA1) to trigger calcium signaling, thereby activating the ERK and PI3KPKB/Akt pathways (Takahashi et al

N Engl J Med 373: 21032116, 2015
