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From a clinical perspective, reducing ZnT8 transport activity or down-regulating its cellular expression is proposed as an anti-diabetogenic strategy, mimicking the protective effect of SLC30A8 haploinsufficiency in humans
10.3389/fphar.2025.1588857 141
This can be done by binding to the enzyme's active site or by indirectly acting as an antioxidant and scavenging free radicals

J., Leonard, G
In 2026, two peptide-based compounds dominate scientific discussion: retatrutide vs tirzepatide
