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Furthermore, hypoxia-induced endogenous LOX expression has been applied in the repair of de novo multiple musculoskeletal tissues (i.e., cartilage, meniscus, tendons, and ligaments) as important regenerative strategies, which is mainly mediated through mechanisms of hypoxia-induced enhanced PYR crosslinking and increased tensile properties of collagen-rich tissues (Makris et al., 2014)
doi:10.1016/j.jacbts.2021.11.004 6
However, these ex vivo fluorescence markers do not yield reproducible information
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Silymarin in the prevention and treatment of liver diseases and primary liver cancer
