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Therefore, GST activity results in irreversible GSH depletion leading to decreased levels of GSH if not to de novo GSH biosynthesis

Several biological effects have been described for carnosine and its precursor beta-alanine

10.1152/ajpheart.2001.281.3.H1422 [DOI] [PubMed] [Google Scholar] Van Remmen H., Ikeno Y., Hamilton M., Pahlavani M., Wolf N., Thorpe S.R., Alderson N.L., Baynes J.W., Epstein C.J., Huang T.T., et al

Over time, this can weaken the integrity of existing strands while impeding new growth

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