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Pachymic acid (PA), a lanolin-type triterpenoid, demonstrates ferroptosis-inhibitory properties by reducing MDA, ROS, and Fe 2 levels while upregulating GSH, SLC7A11, and GPX4, thereby alleviating MIRI [92]

On the contrary, the defect sites injected with GSH-high hES-MSCs showed the greatest regenerative effects on articular cartilage, with dense Safranin-O staining, indicating that more hyaline cartilage and proteoglycans were generated on the defects (Fig

Gven et al

Therefore, we first conducted preclinical studies in healthy and T2DM individuals to confirm these previous studies findings on the differences between healthy and T2DM individuals immune responses against an in vitro M

10.1164/rccm.200806-851OC Summary Keywords glutathione peroxidase, redox balance, oxidative stress, inflammation, iron death Citation Pei J, Pan X, Wei G and Hua Y (2023) Research progress of glutathione peroxidase family (GPX) in redoxidation