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The resulting mitochondrial dysfunction further exacerbates oxidative stress and impairs cellular energy production, creating a vicious cycle of damage and dysfunction [178]

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These findings suggest that IGF-1 could be a valuable therapeutic agent for treating tendon injuries in clinical settings

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Human research, though preliminary, shows encouraging results: PCOS patients taking curcumin (1,500 mg/day) for 12 weeks significantly lowered fasting blood glucose and insulin levels (237)