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commonly employed natural polymers include chitosan, cellulose, and gelatin, whereas PLA and PLGA are widely utilized synthetic alternatives (24)

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Under normoxic conditions approximately 75% of erythrocyte glucose is shunted to the pentose phosphate pathway for the production of NADPH in order to efficiently couple this with the anti-oxidant glutathione (GSH) cycle, thereby limiting the amount of reactive oxygen species (ROS) in the erythrocyte