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ChREBP-deficient mice have decreased lipogenesis as well as reduced expression of ACC, ACLY, and FASN, but unchanged levels of SREBP-1c, suggesting that ChREBP and SREBP proteins are both required for the regulation of lipid synthesis genes (137)

Can J Gastroenterol Hepatol

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For example, one patient in the testing set who has undetectable CSF hypocretin levels (below 40 pg/ml) but no history of cataplexy should be diagnosed as NT1 according to our knowledge of hypocretin deficit

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