acetaminophen depletes glutathione mechanism Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update Fasting depletes Glutathione, turning "safe"

Propylthiouracil (PTU): Mechanism of Action: Similar to MMI, PTU also inhibits thyroid peroxidase but additionally reduces peripheral conversion of T4 to T3

Because conjugation of the electrophilic AFB 1 -8,9-epoxide with GSH is an alternative fate to binding to nucleophilic centers in cellular macromolecules, GSTs play a critical role in the protection of tissues from the deleterious effects of bioactivated AFB 1 , and tissues vary considerably in both GST concentration and distribution of specific GST isoforms

In contrast, the crucial role of alanine in T cells activation and macrophage-mediated phagocytosis can possibly support the function of Teffs cells against distinct tumors and the antitumor role of macrophage-mediated phagocytosis against tumor cells that detached from the tumor mass [128, 129]

But Lenny, for the review, what do you got

Characteristics of glutathione biosynthesis by freshly isolated rat kidney cells