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Pediatr Clin N Am 33(3):691701 Rumack BH (2002) Acetaminophen hepatotoxicity: the first 35 years

nucleatum -treated mice are highly susceptible to DSS-induced colitis (88)

Assessment of the in vivo toxicity of gold nanoparticles

doi: 10.1080/15226514.2018.1460307 110 ZakiS

Although various studies on copper-induced cell death have shown promising results, there still remain several challenges, such as how the aggregation of fatty acylated proteins triggers cell death, optimizing the performance of copper regulators and reducing their side effects, determining the mode of death induced by copper overload and deficiency, gaining a comprehensive understanding of the roles of copper in the mitochondria, and whether copper ion carriers can selectively deliver drugs to hypertrophic myocardial tissues through drug delivery systems (183)
