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In lower concentrations, urea can be beneficial to the cell providing an extra nitrogen source, but in larger concentrations, urea can form lethal ethyl carbamate, which is genotoxic to cells [199]

Cell 186 , 243278 (2022)

Unlike metformin, which interferes with calcium-dependent B12 absorption in the ileum, GLP-1 receptor agonists do not have a known mechanism that would directly impair B12 absorption or metabolism

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Lancet 403 (10423), 283292
