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In addition, the nasal cavity contains immunoglobulins such as IgS, which can combine with peptide drugs to form complexes (Kakad et al., 2015), making it difficult for the drug to pass through the nasal mucosa if the size exceeds 500 nm
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However, as with all of the supplements mentioned in this guide, the potential effects will take time to appear anywhere from a few weeks to a couple of months

Kocsis, James W

The primary endpoint was the clinical benefit rate after 18 weeks of treatment
