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Nonetheless, whether the specific mechanism of this is related to the transdifferentiation of VSMCs to a bone-like phenotype, loss in SMC lineage markers, enhanced pro-calcific microRNAs, increased intracellular calcium level, apoptosis, or aberrant DNA damage response (DDR) requires further investigation

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Trimethylamine N-oxide (TMAO) is a metabolite produced through a well-characterized meta-organismal pathway

Cancer and immunotherapy: a role for microbiota composition

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