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Description
Another promising approach involves developing a new generation of non-toxic or low-toxic nanoparticles or innovative construction strategies
Multidrug Resistance-associated Protein 1 (MRP1) and MRP2, of the ABC (ATP-Binding Cassette)-type subfamily C transporters, transport oxidized glutathione and glutathione S-conjugates when expressed in yeast 58,59 and might be involved in their transport from the cytosol into the vacuole in plants
Kometani T, Yoshino I, Miura N, Okazaki H, Ohba T, Takenaka T, Shoji F, Yano T, Maehara Y (2009) Benzo[a]pyrene promotes proliferation of human lung cancer cells by accelerating the epidermal growth factor receptor signaling pathway
Future work should focus on validating its effects on key signaling pathways (e.g., NF-B, MAPK) and confirming these observations in vitro using human skin cell models
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