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Description
The dose reduction during a drug holiday are from 10%-100%, including by way of example only 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, and 100%

The stem itself binds a pocket in the thumb of NS5B, an interaction reminiscent of the one reported between NS5 and stem-loop A of dengue virus 77 (Supplementary Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Stadtman ER

doi: 10.1016/0305-7372(90)90048-K
