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It is important for maintaining normal circadian rhythms and sleep-wake cycles

Here we ask whether killifish undergo age-dependent changes in the main hematopoietic organ (kidney marrow), which may contribute to systemic aging

TM represents a promising multifaceted approach to cancer therapy, involving mechanisms such as angiogenesis inhibition, interference with copper-dependent enzyme functions, apoptosis induction, immune modulation, and overcoming chemotherapy resistance

Combining global stable-isotope tracing metabolomics and isotopologue similarity networking, the IsoNet technology developed in this study allowed to uncover hundreds of putative unknown metabolic reactions in cellular metabolism

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