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Vitamin B1 is an important coenzyme that helps the body convert food into energy

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Tirzepatide's dual GIP and GLP-1 receptor activation typically produces stronger appetite suppression than semaglutide's GLP-1-only mechanism
[DOI] [PubMed] [Google Scholar] 5.Allen LH, Rosado JL, Casterline JE, Lopez P, Muoz E, Garcia OP, Martinez H

Yes, it is especially helpful in managing diabetic neuropathy