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After 7 days of ageing, the enzyme activity was 13 nmol min 1 mg 1 protein and it decreased by almost 41% after 14 days of ageing

Its prevalence rose 50.4% worldwide between 1990 and 2019 (25.26%38.00%), with the highest rates found in South Asia (33.83%), the Middle East/North Africa (36.53%), and Latin America (44.37%), while Western Europe had the lowest frequency (25.10%) (Younossi et al., 2023)

8 Clinical application prospects of DPP1 inhibitors 8.1 Bronchiectasis Bronchiectasis represents a chronic respiratory disease characterized by permanent and abnormal bronchial dilation, usually secondary to recurrent airway infections and inflammation ( Current clinical practice lacks specific therapies approved for treating bronchiectasis, with clinical management primarily relying on empirical treatment strategies including antibiotic use, airway secretion clearance techniques, and bronchodilator application

Adolph, E

Huang Z, Huang PL, Panahian N, Dalkara T, Fishman MC, Moskowitz MA: Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase