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CoQ10 , a mitochondrial antioxidant, was tested at high doses in early Parkinsons and in Huntingtons and showed no benefit, though it retains a role in blood pressure and in primary CoQ10 deficiency
37 Secondly, biologics prescribed for IBD can also be prescribed for other immuno-inflammation-related diseases such as rheumatoid arthritis, psoriasis and psoriatic arthritis, which were not excluded in the present analysis, therefore such comorbid conditions may also have contributed to the overall results
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The disease involves the progressive loss of dopaminergic neurons in the substantia nigra compacta and also -synuclein inclusions known as Lewy bodies [33]
