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For example, a custom-designed nanocarrier for IL-10 DNA delivery was developed by screening a library of cationic polymers using high-throughput testing in macrophages ( 2.2.2 mRNA delivery RNA-based medicine has emerged as an alternative to DNA-based medicine due to technological breakthroughs such as the Nobel Prize winning development of nucleoside base modifications ( Given the inherent risk of systemic IL-12 administration, it is important that exogenous use of this cytokine be restricted to the local TME

Furthermore, changes in AMPA and kainate receptors have been reported in ASD

More information is provided in the NIDDK health topics, Diabetic Kidney Disease and High Blood Pressure and Kidney Disease