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The role of the H 2-catalytic core interaction was assessed in human PLC 3, where point mutations in H 2 or its binding site on the catalytic core decreased the thermal stability of the enzyme and increased basal activity up to 50-fold over wild-type PLC 3 (Lyon et al., 2011)

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Gut microbiota composition in prediabetes and newly diagnosed type 2 diabetes: a systematic review of observational studies

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For example, proline is the preferred amino acid substrate of Clostridium genus bacteria, while other anaerobes, including Bacteroides , Lactobacillus , Bifidobacterium , and Peptostreptococcus ferment the aromatic amino acids [52] phenylalanine, tryptophan and tyrosine