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This moderate oxidative stress initiates several important mechanisms: Activation of antioxidant systems Ozone stimulates the transcription factor Nrf2, which activates antioxidant response elements (ARE)
Mitochondria and Autophagy Dysfunction in Glucocorticoid-Induced Ocular Hypertension/Glaucoma Mice Model
Free Radic Biol Med 100:6672
Pharmaceuticals 17:322
In CIRS patients, elevated serum MMP-9 levels correlate with symptom intensity and barrier tissue vulnerability, particularly in the gut-brain axis and vascular endothelium
