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Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines

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Our main motivation to generate a C/EBP-based system came from our recent studies where we showed that experimental prevention of uORF-dependent translation re-initiation and the resulting decrease in LIP expression (decrease in LIP/LAP ratio) leads to CR-like metabolic improvements 12,17,29

Pathogenesis and treatment options of cancer related anemia: Perspective for a targeted mechanism-based approach

[9] By decreasing lactic acid buildup you can increase your muscular endurance, decrease muscular fatigue, and increase the amount of muscle cellular damage