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Furthermore, preclinical models showed that CR4056 as a novel I2 ligand analgesic was highly effective against BTZ-induced neuropathy in rats (Meregalli et al., 2012)

Other ways to reduce symptoms include: taking a small dose of antibiotics, which can reduce bacteria in the gut to help prevent the production of trimethylamine taking a laxative to lessen the time that food takes to pass through the digestive tract, which can help reduce the amount of trimethylamine that the gut produces if possible, avoiding situations or activities that cause excessive sweating, such as heavy exercise or emotional upset and stress Certain supplements may help reduce the amount of trimethylamine in a persons urine

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Stay Hydrated: Drink plenty of water throughout the day to prevent dehydration, which can cause fatigue