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Further research could determine the behavioral impact of alcohol metabolism in other brain-specific regions, the effect of different patterns of alcohol intake on this local metabolism, and the timing of developmental alcohol exposure, such as drinking in youth or in utero exposure

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Tolerability and Safety Questions Both candidates are likely to be judged partly on gastrointestinal tolerability: nausea, vomiting, diarrhea, constipation, dose escalation, and discontinuation due to adverse events

Typically, 390 to 400

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