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Hydroxocobalamin 1mg is the standard UK formulation, typically administered every two to three months for maintenance therapy Self-administration requires GP prescription, competency training from practice nurses, and demonstration of proper injection technique Common injection sites include the thigh (vastus lateralis) for both intramuscular and subcutaneous administration with site rotation essential Serious side effects are rare but anaphylaxis requires immediate 999 call

GHK-Cu has a molecular weight of approximately 341 Da as the free tripeptide (before copper coordination), which puts it near but not comfortably below that threshold

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Epub 2008/01/15