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found that signal transducers and activators of transcription 3 (STAT3) promote MYC expression in tumor cells in AML, which in turn regulates the transcription of amino acid transporter SLC1A5, promotes Gln metabolism in AML cells, and oxidative phosphorylation (OXPHOS) of leukemia stem cells (LSCs)

doi: 10.7150/ijbs.41051 102 LiXGracillaDCaiLZhangMYuXChenXet al

doi: 10.3390/pharmaceutics16030397

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HRH2 isoform 1 is 397 amino acids and HRH2 isoform 2 is 359 amino acids