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Intriguingly, the intake of purple grape juice for 8 weeks positively affected diastolic blood pressures, DNA damage and antioxidant status in smokers, mainly greater in Glutathione S-Transferase Mu 1 (GSTM1)-null and GSTT1-present types

A typical cycle lasts eight to twelve weeks followed by a break to prevent desensitization

[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Pietrogrande L, Raimondo E

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The damage typically affects the longest nerves first, producing the classic stocking-and-glove distribution of numbness and pain in feet and hands