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Studies and clinical experience show that lipotropic injections work best when coupled with a calorie-restricted diet, regular resistance or aerobic exercise, and behavior-change coaching rather than as stand-alone therapy

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However, despite these promising advantages, clinical research is still limited, and FDA approval has not been granted

It can be taken together with CoQ10 for energy, as it simplifies the conversion of the coenzyme with an antioxidant function into its active form to protect cells from damage

For this reason, B12 injections are sometimes used to offset the many symptoms of vitamin B12 deficiency, such as fatigue and weakness, poor moods, and low concentration