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Nucleosomal Histone Peptides Endogenous peptide epitopes of histones from nucleosomes induce immune tolerance and promote CD4 + and CD8 + T reg responses, and reduce lupus nephritis and B cell activation in (SWR x NZB) F1 (SNF1) mice, [70, 71, 72] also blocking pathogenic autoimmunity in human SLE

CoQ10selenium combination, -nicotinamide adenine dinucleotide (NADH), and NADH-CoQ10 combination were also found to alleviate fatigue in patients with ME/CFS [129,130,131]