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Description
The in vitro 4T1 model is deprived of major components of the TME, including M2 macrophages and cancer-associated fibroblasts (CAFs), which release factors that increase MMP secretion and alter the invasive characteristics of cancer cells (Chen et al

[DOI] [PubMed] [Google Scholar] 21.Suto D., Sato K., Ohba Y., Yoshimura T., Fujii J
doi: 10.3390/ijms22010268

Its a quick procedure that usually causes minimal discomfort
Thawkar BS, Kaur G (2019) Inhibitors of NF-B and P2X7/NLRP3/Caspase 1 pathway in microglia: novel therapeutic opportunities in neuroinflammation induced early-stage Alzheimers disease