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Why the Mechanism Did Not Translate A fair mechanistic article should not just report the human failure but try to understand it, because the gap between rodent lipolysis and human weight loss is instructive about the biology itself

Zdecydowana wikszo danych pochodzi z bada in vivo przeprowadzonych na modelach mysich i szczurzych, a take z eksperymentw in vitro na hodowlach komrkowych

doi: 10.1021/ja303280r 101 GuoQ.XuS.YangP.WangP.LuS.ShengD.et al

In particular, oxidative stress likely plays a role in insulin resistance, the hallmark of type 2 diabetes that affects insulin secretion and leads to uncontrolled blood sugar, the authors write

What We Know and What We Don't GHK-Cu occupies an unusual position in peptide science
