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& Calbet, J

N -acetyl-aspartate (NAA) as a correlate of pharmacological treatment in psychiatric disorders: a systematic review

Moreover, modified leptin release from adipose tissue, characteristic of obesity, results in leptin resistance and diminished leptin sensitivity, further disrupting hypothalamic-pituitary regulation

While a recent study demonstrated a lack of correlation between GSH levels in the putamen and body status in patients with PD, whole blood GSH was shown to be sensitive to aging with concentrations being correlated to severity of PD progression (Mischley et al., 2016)

The rationale is theoretical and based on mitochondrial effects