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In addition, LPS stimulation increased NOX1 mRNA expression as well as that of SOD2, IL-6, IL-8, IL-25, and IL-33 ( Figures 7E, F )

6 - hydroxy - FAD is not only an active co - factor of FSP1 but also an effective radical - trapping antioxidant that can directly inhibit ferroptosis in cells (Lv et al., 2023)

Our review fills this gap by uniquely structuring the discussion around five key pillars of pulmonary vascular remodeling in PH: PASMC proliferation, immune-inflammatory responses, pulmonary fibrosis, abnormal vasoconstriction, and PASMC ferroptosis

Nasiri M, Farhangi H, Badee Z, Ghasemi A, Golsorkhi M, Ravanshad Y, Azarfar A

Valero-Mendoza, A