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Long-term Use and Zinc Some evidence suggests that long-term, high-dose glutathione use may lower zinc levels in the body

J Psychopharmacol 20(5):611621 Oluwasola A et al (2023) Effect of acute administration of ethanol extract of Cannabis sativa leaf on oxidative stress biomarkers in male and female Wistar rats

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By stimulating the innate immune system and encouraging the infiltration of inflammatory cells, interleukin-1 (IL-1) is an essential mediator of inflammation, host defense, and acute-phase responses