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In tests conducted on type 2 diabetic mice, hydrophilic APGS was found to have higher bioavailability and a more favorable effect on diabetes and inflammation, attributing this to its favorable pharmacokinetic behavior and water solubility [102]

The PD-relevant neurotoxin salsolinol induces ferroptosis by upregulating ACSL4 expression (54)

Therapeutic Adv Gastroenterol 16:17562848231191664 Park NW, Lee ES, Ha KB, Jo SH, Kim HM, Kwon M-H, Chung CH (2023b) Umbelliferone ameliorates hepatic steatosis and lipid-Induced ER stress in High-Fat Diet-Induced obese mice

Nucleic Acids Res 42:D503509 Reis ES, Mastellos DC, Hajishengallis G, Lambris JD (2019) New insights into the immune functions of complement

10.3389/fmicb.2022.1005842 88 WangH.LiuC.ZhaoY.GaoG