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NNMT had previously been identified as upregulated in obese adipose tissue, several solid tumours, and ageing tissue more broadly, where its activity correlates with depleted SAM and elevated 1-methylnicotinamide (MNA)

Nat Genet 42: 1000-1004

Progress photos taken under consistent lighting conditions help visualize changes

The plasma will be centrifuged at approximately 700 g at room temperature for 10 min, separated and transferred into storage vials, and stored at 70 before analysis