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The release of LDH, which is widely used as an auxiliary method to detect pyroptosis [16], also increased in the culture supernatants of hypoxia macrophages, indicating that pyroptosis mediated by GSDMD occurred after HLI

& Takada, H

Randomization was performed by a co-investigator who was not present during the testing to ensure the double-blind nature of the study
Interestingly, IL-6 stimulation enhances JAK1-mediated phosphorylation of SIRT1 (95)

10.1038/nrd2466 59 MaioranaA.ODriscollG.TaylorR.GreenD