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Scratch-wound assays are useful and widely used, but they require careful controls because wound closure can be affected by both migration and proliferation

It does so by also potentiating FSH actions on granulosa cells, and it was demonstrated that the IGFR was absolutely required for FSH-mediated activation of the PI3K/Akt pathway which is a pro-survival cascade, and subsequent granulosa cell differentiation (59, 60)

Its ability to support neurogenesis, enhance synaptic plasticity, protect against neurodegeneration, regulate neurotransmitters, and enhance learning and memory highlights its potential advantages for cognitive function

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