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Cell Rep (2018) 25:20619.e4
Linking pathogenic mechanisms of alcoholic liver disease with clinical phenotypes
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Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor
These include individuals with a personal or family history of medullary thyroid carcinoma, those diagnosed with multiple endocrine neoplasia syndrome type 2, patients with severe gastrointestinal conditions such as gastroparesis, individuals who are pregnant or breastfeeding, and patients with severe renal impairment
