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Fraction of Drug Excreted The fraction of drug excreted unchanged in the urine (f e ) is equal to the ratio of the total amount of unchanged drug excreted in the urine u , to the fraction of the dose absorbed, FD 0 : It was found that (f e ) is also equal to ke/k: A single oral dose of antibiotic (500 mg) was given
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some toxicants, such as mycotoxins, sprouted potatoes, and arecoline, are often ignored
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