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The shortage of ATP production would lead to cytoskeletal remodeling and calcium cycling prolongation, which weakens cardiomyocyte contraction (Fig
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doi: 10.2337/dc24-S012 Summary Keywords exerkines, diabetic retinopathy, anti-inflammatory effect, antioxidant, neuroprotection, therapeutic strategies Citation Zhu J (2026) Exerkines in diabetic retinopathy: from mechanisms to therapeutic prospects

Polysulfide metabolizing enzymes influence SqrR-mediated sulfide-induced transcription by impacting intracellular polysulfide dynamics