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In other words, long-term calorie restriction doesnt appear to directly reduce serum IGF-1 in humans (18)

A Phase I safety study and a Phase II ulcerative colitis trial of the BPC-157 formulation PL 14736 were conducted by the Croatian pharmaceutical company Pliva, but full peer-reviewed Phase II efficacy results have not been published

doi: 10.1016/s0959-8049(97)00203-7

Signal transduction mechanisms underlying growth hormone receptor action

Anyone with a hormone-sensitive condition, anyone pregnant or nursing, and anyone on prescription metabolic or diabetes medication sits outside what the research can speak to at all