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Description
It has been suggested [22] that while the biliary excretion of GSH is a passive phenomenon directly related to the intrahepatic concentrations of GSH, the excretion of GSSG into the bile is a carrier-mediated process against a steep concentration gradient

This can be seen histologically as ghost vessels and on fluorescein angiography of the retinal circulation localized areas appear where the inner retinal capillary blood supply is lost

The relevance of this phenomenon in RBC aging in vivoto the extent this may result from/contribute to processes of age-related aberrant erythropoiesis and age-related comorbidities remains to be determined

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Combined Targeting of STAT3 and STAT5: A Novel Approach to Overcome Drug Resistance in Ph+ Cml
