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M.MilosevicI.Gulyas-KovacsA.RiedelD.SorensenJ

When administered as a nasal spray, it could bypass the blood-brain barrier, allowing the peptide to act directly on brain tissues

The highest single charged state for the precursor ion (656.34 m / z ) and the five product ions (509.26 m / z , 492.23 m / z , 435.21 m / z , 279.11 m / z , 222.12 m / z ) were used to monitor the internal standard

Here, we aim to introduce the potential involvement of reactive astrocytes in AD pathology, characterized by the expression of distinct markers such as GFAP, TSPO, and MAO-B

As expected, the former diseased cells further manifested enhanced HNEylated proteomes (Extended Data Fig