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Although some studies have shown that inhibiting ferroptosis has an anti-depressive function, the specific mechanisms by which ferroptosis is regulated in MDD remain to be fully elucidated

Antioxidants counteract neural oxidative damage linked to depressive severity

The major findings were a reduced C3 activation both at plasma and local level, a drop of total serum haemolytic activity, with lower degree of inflammatory cell infiltration and tissue damage (69)

Conversely, depletion of USP11 inhibited H1299 cell proliferation and induced ferroptosis [143]

These findings suggest that shrimp-allergic individuals generally have a higher reaction threshold, though further challenges are needed to confirm these results [105]