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On the other hand, it promotes -syn aggregation by increasing thioredoxin-interacting protein (TXNIP), thereby inhibiting autophagy flux and mitochondrial autophagy, which accelerates dopaminergic neuron apoptosis and worsens PD progression [78]

doi: 10.1016/j.freeradbiomed.2018.01.010 157 ChigbrowMNelsonM

Lee W-J, Lee S-T, Shin Y-W, Lee HS, Shin H-R, Kim D-Y, et al

de Almeida MV Novel Gold(I) Complexes with 5-Phenyl-1,3,4-Oxadiazole-2-Thione and Phosphine as Potential Anti-cancer and Antileishmanial Agents

Subsequently, 20 l of trichloroacetic acid was added
